This page contains the list of our recent publications in chronological order: 20182017, 2016, 2015. Click here for a complete list of our journal articles, conference proceedings, and invited talks. Contact us for a free print if you don’t have access to the online articles.


Zhentian Lei, Bonnie S Watson, David V. Huhman, Dongsik Yang, Lloyd W. Sumner. Large-Scale Profiling of Saponins in Different Ecotypes of Medicago truncatula. Frontiers in Plant Science, 2019, 10, 850, 1-12, doi: 10.3389/fpls.2019.00850.

Brittney L. Marshall, Yang Liu, Michelle J. Farrington, Jiude Mao, William G. Helferich, A. Katrin Schenk, Nathan J. Bivens, Saurav J. Sarma, Zhentian Lei, Lloyd W. Sumner, Trupti Joshi, Cheryl S. Rosenfeld. Early Genistein Exposure of California Mice and Effects on Microbiota-Gut-Brain Axis. Journal of Endocrinology, 242, 139–157. doi: 10.1530/JOE-19-0214. PMID: 31189133.

Chan Man Ha, Dennis Fine, Anil Bhatia, Xiaolan Rao, Nancy Engle, Daniel J. Wherritt, Timothy Tschaplinsk, Lloyd W. Sumner, and Richard A. Dixon. “Ectopic Defense Gene Expression Is Associated with Growth Defects in Medicago truncatula Lignin Pathway Mutants”. Plant Physiology, 181(1) 63-84.

Vered Tzin, John H. Snyder, Dong Sik Yang, David V. Huhman, Bonnie S. Watson, Stacy N. Allen, Yuhong Tang, Karel Miettinen, Philipp Arendt, Jacob Pollier, Alain Goossens, Lloyd W. Sumner. Integrated Metabolomics Identifies CYP72A67 and CYP72A68 Oxidases in the Biosynthesis of Medicago truncatula Oleanate Sapogenins. Metabolomics, special issue on Plant Metabolomics, 2019, 15 (6) 85. ¬¬¬¬doi: 10.1007/s11306-019-1542-1. PMID: 31144047

Poudel AN, Holtsclaw RE, Kimberlin A, Sen S, Zeng S, Joshi T, Lei Z, Sumner LW, Singh K, Matsuura H, Koo AJ. 12-Hydroxy-jasmonoyl-L-isoleucine is an active jasmonate that signals through CORONATINE INSENSITIVE 1 and contributes to the wound response in Arabidopsis. Plant Cell Physiol. 2019 May 31. pii: pcz109. doi: 10.1093/pcp/pcz109. [Epub ahead of print] PMID: 31150089.

Anil Bhatia, Saurav J. Sarma, Zhentian Lei, Lloyd W. Sumner. UHPLC-QTOF-MS/MS-SPE-NMR is a solution to the metabolomics grand challenge of higher-throughput, confident metabolite identifications. Methods in Molecular Biology, NMR-Based Metabolomics, Eds. G.A. Nagana Gowda and Dan Raftery. Humana, New York, NY, 2019. ISBN 978-1-4939-9689-6 and

Danh C Vu; Mark V Coggeshall; Zhentian Lei; Lloyd Sumner, Chungho Lin, Identification and Quantification of Phytosterols in Black Walnut Kernels. Journal of Food Composition and Analysis, 2019, 75, 61-69.


Zhentian Lei, Barbara W. Sumner, Anil Bhatia, Saurav J. Sarma and Lloyd W. Sumner. UHPLC-MS Analyses of Plant Flavonoids. Current Protocols in Plant Biology, 2018, e20085. doi: 10.1002/cppb.20085.

Zhentian Lei, Clayton Kranawetter, Barbara Sumner, David Huhman, Daniel J. Wherritt, Andrew L. Thomas, and Lloyd W. Sumner, Metabolomics of two pecan cultivars provides insights into scab resistance. Metabolites, 2018, 8 (4) 56.

Victoria J. Vieira-Potter, Tzu-Wen L. Cross, Kelly S. Swanson, Saurav J. Sarma, Zhentian Lei, Lloyd W. Sumner, Cheryl S. Rosenfeld. Soy-Induced Fecal Metabolome Changes in Ovariectomized and Intact Female Rats: Relationship with Cardiometabolic Health. Scientific Reports, 2018, 8,16896, 1-12. DOI:10.1038/s41598-018-35171-3.

Khanh-Van Ho, Zhentian Lei, Lloyd W. Sumner, Mark Coggeshall, Hsin-Yeh Hsieh, George Stewart, Chung-Ho Lin. Identifying Antibacterial Compounds in Black Walnuts (Juglans nigra) Using a Metabolomics Approach. Metabolites, 2018, 8 (4) 58.

Anna Serra-Clusellas, Laura De Angelis, Lin Chung-Ho, Phuc Vo, Mohamed Bayati, Zhentian Lei, Lloyd W. Sumner, Nathalia Braga, Luis R. Pizzio, Jorge D. Stripeikis, Julián A. Rengifo-Herrera, María M. Fidalgo de Cortalezzi. Abatement of 2,4-D by H2O2 Solar Photolysis and solar photo-Fenton-like Process with Minute Fe(III) Concentrations. Water Research, 2018, 144, 572-580. DOI: 10.1016/j.watres.2018.07.072.

Cheryl S. Rosenfeld, Angela B. Javurek, Sarah A. Johnson, Zhentian Lei, Lloyd W. Summer, Rex A. Hess, Seminal Fluid Metabolome and Epididymal Changes After Antibiotic Treatment in Mice, Reproduction, Mar2018, 156(1) 1-10.

Qiu, Feng; Lei, Zhentian; Sumner, Lloyd W. MetExpert: An Expert System to Enhance Gas Chromatography‒Mass Spectrometry-Based Metabolite Identifications. In-press, Special Metabolomics issue of Analytica Chemica Acta, 2018, 1037, 316-326.

Kota Kera, Dennis Fine, Daniel Wherritt, Yoshiki Nagashima, Norimoto Shimada, Takeshi Ara, Yoshiyuki Ogata, Lloyd W. Sumner, and Hideyuki Suzuki. Pathway-Specific Metabolome Analysis with 18O2-Labeled Medicago truncatula via a Mass Spectrometry-Based Approach. Metabolomics, 2018, 14(5):71. doi: 10.1007/s11306-018-1364-6.


Feng Qiu, Zhentian Lei, and Lloyd W. Sumner. MetExpert: An Expert System to Enhance Gas Chromatography‒Mass Spectrometry-Based Metabolite Identifications. Analytica Chimica Acta, in press; doi: 10.1016/j.aca.2018.03.052


Bibi Rafeiza Khan, Daniel J. Wherritt, David V. Huhman, Lloyd W. Sumner, Kent D. Chapman, and Elison B. Blancaflor. Malonylation of Glucosylated N‐Lauroylethanolamine: A New Pathway that Determines N‐Acylethanolamine Metabolic Fate in Plants, Journal of Biological Chemistry, submitted.

Bonnie S. Watson, Daniel J. Wherritt, David V. Huhman, Derek Nedveck, Dennis D. Fine, Peter Tiffin, Nevin Young, and Lloyd W. Sumner. A Novel M. truncatula DDMP‐Transferase (MtDPT) Plays a Key Role in Saponin Biosynthesis. Nature Plants, in revision.

Srinivasa Rao Uppalapatia, Upinder S. Gill, Lina Gallego‐Giraldo, Yasuhiro Ishiga, Wensheng Li, Lloyd W. Sumner, Richard A. Dixon, and Kirankumar S. Mysore. Targeted Lignin Modification Induces Tolerance to Soil‐Borne Fungal Pathogens in Alfalfa. New Phytologist, submitted.

Feng Qiu, Dennis D. Fine, Daniel J. Wherritt, Zhentian Lei, and Lloyd W. Sumner. PlantMAT: A Metabolomics Tool for Predicting the Metabolic Potential of a System and for Large‐scale Metabolite Identifications. Analytical Chemistry, 2016, 88, 11373-11383; doi: 10.1021/acs.analchem.6b00906.

Sisi Geng, Biswapriya Biswavas Misra, Evaldo de Armas, David V. Huhman, Hans T. Alborn, Lloyd W. Sumner, and Sixue Chen. Jasmonate‐Mediated Stomatal Closure Under Elevated CO2 Revealed by Time‐Resolved Metabolomics, Plant Journal, in‐press.

Arthur S. Edison, Robert D. Hall, Christophe Junot, Peter D. Karp, Irwin J. Kurland, Robert Mistrik, Laura K. Reed, Kazuki Saito, Reza M. Salek, Christoph Steinbeck, Lloyd W. Sumner, and Mark R. Viant. The Time Is Right to Focus on Model Organism Metabolomes. Metabolites, 2016, 6, 8; doi: 10.3390/metabo6010008.


Avinash C. Srivastava, Fang Chen, Tui Ray, Sivakumar Pattathil, Maria J Peña, Urku Avci, Hongjia Li, David V. Huhman, Jason Backe, Breeanna Urbanowicz, Jeffrey S. Miller, Mohamed Bedair, Charles E. Wyman, Lloyd W. Sumner, William S. York, Michael G. Hahn, Richard A. Dixon, Elison B. Blancaflor, and Yuhong Tang. Loss of Function of Folylpolyglutamate Synthetase 1 Reduces Lignin Content and Improves Cell Wall Digestibility in Arabidopsis. Biotechnology Biofuels, 2015 Dec 21;8:224; doi: 10.1186/s13068‐015‐0403‐z.

Daniel Abate‐Pella, Dana M. Freund, Yan Ma; Yamil Simon‐Manso, Juliane Hollender, Corey D. Broeckling, David V. Huhman, Oleg V. Krokhin, Dwight R. Stoll, Adrian D. Hegeman, Tobias Kind, Oliver Fiehn, Emma L. Schymanski, Jessica E. Prenni, Lloyd W. Sumner, and P. G. Boswell. Retention Projection Enables Accurate Calculation of Liquid Chromatographic Retention Times Across Labs and Methods, Journal of Chromatography A, 2015 Sep 18;1412:43‐51; doi: 10.1016/j.chroma.2015.07.108.

Wenchao Zhang, Zhentian Lei, David Huhman, Lloyd W. Sumner, and Patrick X. Zhao. MET‐XAlign: A Metabolite based Cross‐Alignment Tool for LC/MS based Comparative Metabolomics. Analytical Chemistry, 2015 Sep 15;87(18):9114‐9.

Zhentian Lei, Li Jing, Feng Qiu, Hua Zhang, David Huhman, Zhiqin Zhou, and Lloyd W. Sumner. Construction of a UHPLC‐Tandem Mass Spectral Library of Plant Natural Products and Comparative Spectral Analyses. Analytical Chemistry, 2015, 87(14):7373‐7381.

Taehyong Kim, Kate Dreher, Ricardo Nilo‐Poyanco, Insuk Lee, Oliver Fiehn, Bernd Markus Lange, Basil J. Nikolau, Lloyd W. Sumner, Ruth Welti, Eve S. Wurtele, and Seung Y. Rhee. Patterns of metabolite changes identified from large‐scale gene perturbations in Arabidopsis thaliana using a genome‐scale metabolic network. Plant Physiology, 2015 April; 167:1685-1698.

Bonnie S. Watson, Ewa Urbanczyk‐Wochniak, Mohamed F. Bedair, David V. Huhman, Stacy N. Allen, Yuhong Tang, and Lloyd W. Sumner. Integrated Metabolomics and Transcriptomics Reveal Enhanced Specialized Metabolism in Medicago truncatula Root Border Cells. Plant Physiology, 2015, 167(4):1699‐1716.

Li Jing, Zhentian Lei, Guiwei Zhang, Alan Cesar Pilon, David V. Huhman, Rangjin Xie, Wanpeng Xi,
Zhiqin Zhou, and Lloyd W. Sumner. Metabolite profiles of Chinese native Citrus species and their
taxonomic implications. Metabolomics, 2015, 11(4); doi: 10.1007/s11306‐014‐0751‐x.

Lloyd W. Sumner, Zhentian Lei, Basil J. Nikolau, Kazuki Saito. Modern Plant Metabolomics: Advanced Natural Product Gene Discoveries, Improved Technologies, and Future Prospects. Natural Product Reports, 2015, 32, 212-229; doi: 10.1039/c4np00072b[cover article]

Lloyd W. Sumner, Mark Styczynski, John McLean, Oliver Fiehn, Georg Jander, James Liao, Susan Sumner, Philip Britz‐McKibbin, Ruth Welti, A. Daniel Jones, Peter Dorrestein, Dan Bearden, and Rima Kaddurah‐Daouk. Introducing the USA Plant, Algae and Microbial Metabolomics Research Coordination Network (PAMM‐NET). Metabolomics, 2015, 11(1):3‐5.